Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 16/20 | 0.58 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1728860 | 0.99 | F2R (0.59) | F2RIRAK4KDM4ENPC1MAPT | |
| SCHEMBL14468955 | 0.91 | F2R (0.51) | F2RIRAK4 | |
| Bromide SCHEMBL1732001 | 0.91 | F2R (0.51) | F2RIRAK4 | |
| Bromide SCHEMBL1729420 | 0.91 | F2R (0.70) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731526 | 0.91 | F2R (0.61) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449151 | 0.90 | F2R (0.59) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730044 | 0.90 | F2R (0.49) | F2RIRAK4 | |
| Bromide SCHEMBL1730396 | 0.90 | F2R (0.60) | F2RKDM4ENPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1732220 | 0.89 | F2R (0.69) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731207 | 0.89 | F2R (0.59) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |