Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.54 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730338 | 0.99 | F2R (0.54) | F2RTYK2KDM4ENPC1MAPT | |
| SCHEMBL14468891 | 0.91 | F2R (0.47) | F2RTYK2LMNA | |
| Bromide SCHEMBL1732211 | 0.89 | F2R (0.53) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449142 | 0.88 | F2R (0.69) | F2RKDM4EMAPTLMNA | |
| Bromide SCHEMBL1731462 | 0.88 | F2R (0.52) | F2RTYK2KDM4ENPC1MAPT | |
| Bromide SCHEMBL1729157 | 0.88 | F2R (0.69) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449151 | 0.87 | F2R (0.59) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730396 | 0.87 | F2R (0.60) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449120 | 0.86 | F2R (0.53) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729568 | 0.86 | F2R (0.58) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |