Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545074 | 1.00 | ALDH1A1 (0.61) | ALDH1A1THRBLMNAPKMMAPT | |
| SCHEMBL6544510 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTKMT2AGAA | |
| SCHEMBL6544508 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTKMT2AGAA | |
| SCHEMBL6544284 | 0.91 | GAA (0.63) | ALDH1A1THRBLMNAMAPTGAA | |
| SCHEMBL6544288 | 0.91 | GAA (0.63) | ALDH1A1THRBLMNAMAPTGAA | |
| SCHEMBL6544737 | 0.90 | ALDH1A1 (0.57) | ALDH1A1THRBLMNAPKMMAPT | |
| SCHEMBL6544741 | 0.90 | ALDH1A1 (0.57) | ALDH1A1THRBLMNAPKMMAPT | |
| SCHEMBL6544359 | 0.89 | GAA (0.50) | ALDH1A1THRBMAPTKMT2AGAA | |
| SCHEMBL6544363 | 0.89 | GAA (0.50) | ALDH1A1THRBMAPTKMT2AGAA | |
| SCHEMBL6544461 | 0.88 | GAA (0.52) | ALDH1A1THRBLMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140819-B1 | ALFA-SULFENIMINO ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6479550-B1 | α-sulfenimino acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1140819-A1 | ALFA-SULFENIMINO ACID DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042007-A1 | ALFA-SULFENIMINO ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |