Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215126 | 0.96 | FOLH1 (0.60) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL3843262 | 0.96 | FOLH1 (0.60) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL3223579 | 0.91 | FOLH1 (0.53) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL4814393 | 0.86 | FOLH1 (0.60) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL22689761 | 0.85 | FOLH1 (0.59) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL1455499 | 0.84 | FOLH1 (0.62) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL1455498 | 0.84 | FOLH1 (0.62) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL3460653 | 0.84 | FOLH1 (0.62) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL22689842 | 0.83 | SLC6A5 (0.59) | FOLH1SLC6A5GNPATSLC15A2GSR | |
| SCHEMBL29539958 | 0.83 | FOLH1 (0.57) | FOLH1SLC6A5GNPATSLC15A2GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377542-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | Pharmacor Inc. (CA) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002064551-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | PHARMACOR INC. (CA) | 2002-08-22 | — | — | WO | disclosed |