Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545179 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544305 | 0.91 | GAA (0.55) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544306 | 0.91 | GAA (0.55) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544298 | 0.91 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544299 | 0.91 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6812586 | 0.90 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6812591 | 0.90 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544465 | 0.90 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544462 | 0.90 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6544887 | 0.88 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140819-B1 | ALFA-SULFENIMINO ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6479550-B1 | α-sulfenimino acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1140819-A1 | ALFA-SULFENIMINO ACID DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042007-A1 | ALFA-SULFENIMINO ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |