Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399166 | 1.00 | STS (0.38) | STSSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6399154 | 1.00 | STS (0.38) | STSSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6545132 | 0.90 | MEN1 (0.41) | MEN1KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL6399556 | 0.90 | MEN1 (0.41) | MEN1KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL6399561 | 0.90 | MEN1 (0.41) | MEN1KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL6398961 | 0.83 | MAPK1 (0.47) | STSSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6399653 | 0.79 | STS (0.41) | STSSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6399655 | 0.79 | STS (0.41) | STSSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6399650 | 0.79 | STS (0.41) | STSSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL6544709 | 0.78 | BCHE (0.36) | SMN1; SMN2HTTKMT2APTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375465-A9 | CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF | Eisai Co., Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1375479-A1 | PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |