Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAOA | P21397 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309620 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL11555252 | 0.82 | CYP3A4 (0.65) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL11319802 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL11316334 | 0.81 | MCL1 (0.45) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL6993046 | 0.81 | MCL1 (0.45) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL10336302 | 0.80 | MAPK1 (0.46) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL11308343 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL10405325 | 0.80 | MCL1 (0.44) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL11308490 | 0.79 | MCL1 (0.46) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL8416177 | 0.78 | CYP3A4 (0.64) | KDM4EALDH1A1MAOACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579784-B1 | METHOD FOR PREVENTING RESTENOSIS FOLLOWING RECONFIGURATION OF BODY VESSELS | ADVANCED RES & TECH INST (US) | 1999-11-10 | — | — | EP | claimed |
| EP-1377274-A2 | DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS | QLT Inc. (CA) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083097-A2 | DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS | QLT INC. (CA) | 2002-10-24 | — | — | WO | disclosed |
| US-5473083-A | Skin disorders, cancer, Aids | LEHIGH UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| US-5356929-A | Skin, blood and bone marrow disorders | LEHIGH UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |
| US-4294847-A | 8-Aminoalkyl-4-alkylisopsoralens | THOMAS C. ELDER, INC. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4269851-A | 8-Aminoalkyl-4-alkylpsoralens | THOMAS C. ELDER, INC. (US) | 1981-05-26 | — | — | US | disclosed |