Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405325 | 0.89 | MCL1 (0.44) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL6993046 | 0.87 | MCL1 (0.45) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL11316334 | 0.87 | MCL1 (0.45) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL11308490 | 0.85 | MCL1 (0.46) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL6545566 | 0.82 | KDM4E (0.62) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL11310023 | 0.79 | MAPT (0.42) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL11253029 | 0.79 | MAOA (0.59) | KDM4EMAPK1MAPTGAAMCL1 | |
| SCHEMBL11317544 | 0.78 | ERAP1 (0.42) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL10405403 | 0.78 | KDM4E (0.55) | KDM4EMAPK1MAPTGAAGLA | |
| SCHEMBL11555252 | 0.77 | CYP3A4 (0.65) | KDM4EMAPK1MAPTGAAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269851-A | 8-Aminoalkyl-4-alkylpsoralens | THOMAS C. ELDER, INC. (US) | 1981-05-26 | — | — | US | disclosed |