Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.66 |
| ▸ | PDE4A | P27815 | 18/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545608 | 1.00 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL6545610 | 1.00 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL6546021 | 0.91 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545759 | 0.91 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545648 | 0.91 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545650 | 0.91 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546025 | 0.91 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546264 | 0.89 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545621 | 0.89 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545618 | 0.89 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051172-B1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | claimed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | claimed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | claimed |
| EP-1043994-A4 | METHOD FOR TREATING MULTIPLE SCLEROSIS | SMITHKLINE BEECHAM CORP (US) | 2002-09-11 | — | — | EP | claimed |
| EP-1051172-A4 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2002-08-14 | — | — | EP | claimed |
| US-6369108-B1 | CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD). | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | claimed |
| EP-1051172-A2 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORPORATION (US) | 2000-11-15 | — | — | EP | claimed |
| EP-1043994-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999034797-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-15 | — | — | WO | claimed |
| WO-1999034798-A1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-15 | — | — | WO | claimed |
| EP-0919544-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-02 | — | — | EP | claimed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | claimed |
| EP-1051172-B1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | disclosed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0633776-A4 | — | — | 1995-01-25 | — | — | EP | disclosed |
| EP-0633776-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993019749-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |