Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.66 |
| ▸ | PDE4A | P27815 | 19/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545759 | 1.00 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545648 | 1.00 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546021 | 0.92 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546025 | 0.92 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545610 | 0.91 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545608 | 0.91 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545628 | 0.91 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6820943 | 0.90 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6821339 | 0.90 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7119643 | 0.90 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051172-B1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | claimed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | claimed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | claimed |
| EP-1051172-A4 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2002-08-14 | — | — | EP | claimed |
| US-6369108-B1 | CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD). | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | claimed |
| EP-1051172-A2 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORPORATION (US) | 2000-11-15 | — | — | EP | claimed |
| WO-1999034798-A1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-15 | — | — | WO | claimed |
| EP-0919544-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-02 | — | — | EP | claimed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | claimed |
| EP-1051172-B1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1043994-A4 | METHOD FOR TREATING MULTIPLE SCLEROSIS | SMITHKLINE BEECHAM CORP (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-0919544-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5643946-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5614540-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5602157-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |