Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007471 | 0.85 | KDM4E (0.58) | FLT3MAOAKDM4EALDH1A1LMNA | |
| SCHEMBL5230393 | 0.81 | CA12 (0.42) | FLT3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5163230 | 0.81 | PIM1 (0.58) | MAOAKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL3259550 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL6240383 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL4200612 | 0.79 | FLT3 (0.52) | FLT3MAOAKDM4EALDH1A1HPGD | |
| SCHEMBL6545797 | 0.79 | MAOB (0.58) | FLT3MAOAKDM4EALDH1A1LMNA | |
| SCHEMBL5508121 | 0.78 | CYP2A6 (0.42) | MAOAKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL5233703 | 0.76 | MAOB (0.58) | MAOAKDM4EALDH1A1LMNAGAA | |
| SCHEMBL6242111 | 0.76 | KDM4E (0.41) | FLT3KDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373239-A1 | BENZOFURAN DERIVATIVES | Bayer HealthCare AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079181-A1 | BENZOFURAN DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |