Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 2/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204717 | 0.87 | MAOB (0.46) | MAOBMAOAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4683562 | 0.84 | FLT3 (0.49) | MAOBMAOALMNAFLT3KMT2A | |
| SCHEMBL2323034 | 0.84 | ALDH1A1 (0.50) | MAOBMAOAALDH1A1KMT2AHTT | |
| SCHEMBL6545788 | 0.83 | MAOB (0.60) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL9202218 | 0.82 | CA12 (0.46) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL9798234 | 0.82 | CA12 (0.46) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL28007471 | 0.80 | KDM4E (0.58) | MAOBMAOAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6021921 | 0.80 | CA12 (0.50) | MAOBMAOAALDH1A1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL9797800 | 0.79 | CA12 (0.44) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL6545814 | 0.79 | FLT3 (0.54) | MAOBMAOAALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373239-A1 | BENZOFURAN DERIVATIVES | Bayer HealthCare AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079181-A1 | BENZOFURAN DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |