2-Ethoxyethanol

2-Ethoxyethanol

SCHEMBL6545845

C=CC.C=CC.CCOCCO.OCCO

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.70
TSHR P16473 4/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 2/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethoxyethanol SCHEMBL28745967 0.97 ALDH1A1 (0.74) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL16553503 0.97
Diethylene Glycol Monoethyl Ether SCHEMBL2534798 0.95 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1MEN1KMT2A
Diethylene Glycol Monoethyl Ether SCHEMBL15135606 0.93 ALDH1A1 (0.67) ALDH1A1TSHRMAPK1MEN1KMT2A
Ethylene Glycol SCHEMBL17435069 0.90 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1MEN1KMT2A
Ethylene Glycol SCHEMBL4327458 0.88 ALDH1A1 (0.52) ALDH1A1TSHRMEN1KMT2ATHRB
Ether SCHEMBL1070562 0.87 ALDH1A1 (0.48) ALDH1A1TSHR
Ether SCHEMBL2112315 0.87 ALDH1A1 (0.48) ALDH1A1TSHR
Ether SCHEMBL8958539 0.87 ALDH1A1 (0.48) ALDH1A1TSHR
2-Ethoxyethanol SCHEMBL9616407 0.87 ALDH1A1 (0.82) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1171088-B1 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2004-01-14 EP disclosed
US-6361765-B1 COMPOSITION COMPRISING PARTICULATE ANTIPERSPIRANT ACTIVE, ANHYDROUS LIQUID CARRIER AND STRUCTURANT OR THICKNENER COMPRISING ORGANIC WAX HAVING SPECIFIED MELTING POINT, AT LEAST 60% OF WHICH IS PROVIDED BY ALIPHATIC ESTER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-03-26 US disclosed
EP-1180010-A1 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2002-02-20 EP disclosed
EP-1171088-A1 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2002-01-16 EP disclosed
US-6231841-B1 AN ANTIPERSPIRANT COMPRISING AN ANTIPERSPIRANT ACTIVE, A LIQUID CARRIER AND A STRUCTURANT INCLUDING A STEROL AND AN STEROL ESTER TO THICKEN OR SOLIDIFY THE ANTIPERSPIRANT UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-05-15 US disclosed
WO-2000074640-A1 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2000-12-14 WO disclosed
WO-2000061096-A1 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2000-10-19 WO disclosed