Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639109 | 0.94 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6546749 | 0.92 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9109484 | 0.87 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7405782 | 0.86 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7419191 | 0.86 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7418222 | 0.85 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6821602 | 0.84 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14402617 | 0.83 | PDE4B (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9110958 | 0.81 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6129896 | 0.80 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | claimed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | claimed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | claimed |
| US-5449687-A | 4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compositions and methods thereof | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-12 | — | — | US | claimed |
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0633776-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-0919544-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5643946-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5614540-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5602157-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| US-5449687-A | 4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compositions and methods thereof | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0633771-A4 | COMPOUNDS. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0633771-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993019720-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |