SCHEMBL6545877

SCHEMBL6545877

O=S(=O)(Cl)c1cccc(-c2ccccc2-c2cccc(S(=O)(=O)Cl)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
CA12 O43570 2/20 0.42
PTGS2 P35354 6/20 0.42
PTGES2 Q9H7Z7 2/20 0.40
BRD4 O60885 4/20 0.40
KAT6A Q92794 1/20 0.39
PTGS1 P23219 2/20 0.39
IKBKB O14920 1/20 0.38
NAT1 P18440 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
AKR1C3 P42330 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17667417 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL14120596 0.87 KAT6A (0.50) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL14120393 0.87 CA12 (0.49) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL5890635 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL10408548 0.87 ALDH1A1 (0.56) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL297270 0.85 ALDH1A1 (0.62) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL14120619 0.83 KAT6A (0.53) PTGS2PTGES2KAT6APTGS1
SCHEMBL56599 0.79 ALDH1A1 (0.65) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL11576892 0.79 CA1 (0.42) ALDH1A1CA1CA2CA9CA12
SCHEMBL9766543 0.79 TSHR (0.54) ALDH1A1HSD17B10TDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1380572-A1 POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF Japan Science and Technology Corporation (JP) 2004-01-14 EP claimed
EP-1380572-A1 POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF Japan Science and Technology Corporation (JP) 2004-01-14 EP disclosed