Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546090 | 1.00 | MET (0.68) | METKEAP1NFE2L2MMP3BMP1 | |
| Hydrochloric Acid SCHEMBL5174064 | 0.99 | MET (0.67) | METKEAP1NFE2L2MMP3BMP1 | |
| Hydrochloric Acid SCHEMBL5174079 | 0.99 | MET (0.67) | METKEAP1NFE2L2MMP3BMP1 | |
| Hydrochloric Acid SCHEMBL5173974 | 0.92 | MET (0.70) | METKEAP1NFE2L2MMP3MMP1 | |
| Hydrochloric Acid SCHEMBL5173990 | 0.92 | MET (0.70) | METKEAP1NFE2L2MMP3MMP1 | |
| Hydrochloric Acid SCHEMBL5174656 | 0.91 | MET (0.69) | METKEAP1NFE2L2MMP3MMP1 | |
| Hydrochloric Acid SCHEMBL5174666 | 0.91 | MET (0.69) | METKEAP1NFE2L2MMP3MMP1 | |
| Hydrochloric Acid SCHEMBL5174135 | 0.90 | MET (0.68) | METKEAP1NFE2L2MMP3BMP1 | |
| Hydrochloric Acid SCHEMBL5174131 | 0.90 | MET (0.68) | METKEAP1NFE2L2MMP3BMP1 | |
| Hydrochloric Acid SCHEMBL6782085 | 0.89 | MET (0.61) | METKEAP1NFE2L2MMP3BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1382335-A1 | MEDICINES | Nippon Shinyaku Co., Ltd. (JP) | 2004-01-21 | — | — | EP | claimed |