SCHEMBL6546153

SCHEMBL6546153

CCc1ccccc1CC=Cc1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 9/20 0.50
PTGER3 P43115 9/20 0.50
PTGER2 P43116 9/20 0.50
PTGER1 P34995 7/20 0.50
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
RAB9A P51151 3/20 0.38
KDM4E B2RXH2 2/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MEN1 O00255 1/20 0.37
PABPC1 P11940 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546958 0.87 PTGER4 (0.50) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL6546135 0.82 PTGER4 (0.50) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL2484812 0.81 ALDH1A1 (0.50) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL19231487 0.81 ALDH1A1 (0.50) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL2484811 0.81 ALDH1A1 (0.50) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL6546139 0.79 PTGER1 (0.42) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL29373824 0.77 ALDH1A1 (0.48) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL1276606 0.77 ALDH1A1 (0.48) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL2313488 0.77 ALDH1A1 (0.48) PTGER4PTGER3PTGER2PTGER1TSHR
SCHEMBL6546776 0.76 PTGER4 (0.56) PTGER4PTGER3PTGER2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed