SCHEMBL6546186

SCHEMBL6546186

C=C(c1ccccc1)c1ccc(CC)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.47
PLK1 P53350 1/20 0.44
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
GFER P55789 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
TAS2R14 Q9NYV8 1/20 0.41
GRM2 Q14416 1/20 0.40
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546242 0.91 ALDH1A1 (0.56) TP53ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL2750566 0.88 ALDH1A1 (0.45) TP53ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL6546970 0.83 KMT2A (0.50) ALDH1A1MEN1KMT2APLK1MAPT
SCHEMBL10441340 0.83 HSD17B10 (0.65) TP53ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL6547505 0.83 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ASMN1; SMN2PLK1
SCHEMBL8733948 0.82 MEN1 (0.52) MEN1KMT2AMAPTHTTGFER
SCHEMBL14361865 0.82 TP53 (0.59) TP53ALDH1A1SMN1; SMN2PLK1RXRA
SCHEMBL5991861 0.82 TP53 (0.48) TP53MEN1KMT2AGRM2CYP1A2
SCHEMBL894135 0.81 MEN1 (0.65) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL6546856 0.80 TRPV1 (0.55) ALDH1A1MEN1KMT2APLK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677443-B Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation 中国科学院理化技术研究所 2024-07-16 CN disclosed
CN-115197036-B Method for performing anti-mahalanobis hydrogen carboxylation reaction on photocatalytic olefin compound and carbon dioxide 中国科学院理化技术研究所 2024-01-23 CN disclosed
CN-115677443-A Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation 中国科学院理化技术研究所 2023-02-03 CN disclosed
CN-115197036-A Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis 中国科学院理化技术研究所 2022-10-18 CN disclosed
CN-103947031-B Organic electrolyte and organic electrolyte secondary battery 吉坤日矿日石能源株式会社 2017-07-11 CN disclosed
CN-104025364-B Organic bath and organic bath accumulator 吉坤日矿日石能源株式会社 2017-03-08 CN disclosed
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
US-9419307-B2 Organic electrolyte and organic electrolyte storage battery JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-08-16 US disclosed
US-8933165-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-13 US disclosed
US-20150004484-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-01-01 US disclosed
EP-0114385-B1 ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1987-08-05 EP disclosed
EP-0103868-B1 IMPROVED ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1987-04-08 EP disclosed
US-4618914-A 1,1-DIARYLALKENES; HEAT RESISTANCE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-10-21 US disclosed
EP-0174378-A1 Electrical-insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-03-19 EP disclosed
EP-0158809-A1 Electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-10-23 EP disclosed
US-4543207-A ORGANIC ACID ESTERS, AROMATIC ETHERS, ANIMAL OILS, VEGETABLE OILS,AND AROMATIC OLEFINS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-24 US disclosed
US-4506107-A CAPACITORS, CABLES, TRANSFORMERS, PLASTICS NIPPON PETROCHEMICAL COMPANY, LIMITED (JP) 1985-03-19 US disclosed
US-4493943-A MIXTURES OF DIARYLALKANES AND AROMATIC MONO-OR DI-OLEFINS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-01-15 US disclosed
EP-0114385-A2 Electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-08-01 EP disclosed
EP-0103868-A2 Improved electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-03-28 EP disclosed