SCHEMBL6546345

SCHEMBL6546345

CC(C)c1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.59
MAPK1 P28482 1/20 0.59
MAOB P27338 2/20 0.56
CYP19A1 P11511 1/20 0.56
MAOA P21397 1/20 0.56
PTGS1 P23219 1/20 0.55
PTGS2 P35354 1/20 0.55
EGFR P00533 1/20 0.54
TYR P14679 1/20 0.54
AHR P35869 1/20 0.52
RELA Q04206 3/20 0.50
NFE2L2 Q16236 2/20 0.50
TRPA1 O75762 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 1/20 0.49
CHAT P28329 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16105702 1.00 KDM4E (0.59) KDM4EMAPK1MAOBCYP19A1MAOA
SCHEMBL16105804 1.00 KDM4E (0.59) KDM4EMAPK1MAOBCYP19A1MAOA
SCHEMBL30075786 0.90 TYR (0.64) KDM4EMAPK1PTGS1PTGS2TYR
SCHEMBL23918549 0.90 TYR (0.64) KDM4EMAPK1PTGS1PTGS2TYR
SCHEMBL7840771 0.86 TYR (0.54) KDM4EMAPK1MAOBCYP19A1MAOA
SCHEMBL23332040 0.85 KDM4E (0.59) KDM4EMAPK1PTGS1PTGS2EGFR
SCHEMBL18353270 0.84 RELA (0.50) KDM4EMAPK1MAOBCYP19A1MAOA
SCHEMBL12292310 0.84 RELA (0.50) KDM4EMAPK1MAOBCYP19A1MAOA
SCHEMBL8547188 0.82 KDM4E (0.71) KDM4EMAPK1PTGS2EGFRTYR
SCHEMBL8547187 0.82 KDM4E (0.71) KDM4EMAPK1PTGS2EGFRTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119100923-A Benzenemomod derivative, preparation method and application thereof 武汉英纳氏药业有限公司 2024-12-10 CN claimed
CN-115368518-A Colloidal particle emulsifier and preparation method and application thereof 西南石油大学 2022-11-22 CN claimed
CN-112250546-A Synthesis method of (E) -3, 5-dihydroxy-4-isopropyl stilbene 中山大学 2021-01-22 CN claimed
CN-119100923-A Benzenemomod derivative, preparation method and application thereof 武汉英纳氏药业有限公司 2024-12-10 CN disclosed
CN-115368518-A Colloidal particle emulsifier and preparation method and application thereof 西南石油大学 2022-11-22 CN disclosed
CN-103947031-B Organic electrolyte and organic electrolyte secondary battery 吉坤日矿日石能源株式会社 2017-07-11 CN disclosed
US-9419307-B2 Organic electrolyte and organic electrolyte storage battery JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-08-16 US disclosed
US-20150004484-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-01-01 US disclosed
US-20140370375-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-12-18 US disclosed
EP-2797153-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
EP-2797154-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
US-20140302387-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-10-09 US disclosed
EP-2784868-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-01 EP disclosed
CN-103947031-A Organic electrolyte and organic electrolyte secondary battery JX NIPPON OIL & ENERGY CORP 2014-07-23 CN disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed