Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571160 | 0.97 | IGF1R (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL6546878 | 0.94 | CYP1A2 (0.62) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL28598480 | 0.89 | IGF1R (0.55) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL392911 | 0.89 | ESR1 (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL6546824 | 0.89 | MAOB (0.60) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL5610012 | 0.87 | IGF1R (0.53) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL80498 | 0.87 | ESR1 (0.65) | IGF1RALOX15ACHEESR1ADRA2A | |
| SCHEMBL168031 | 0.87 | ESR1 (0.65) | IGF1RALOX15ACHEESR1ADRA2A | |
| SCHEMBL9678943 | 0.87 | ESR1 (0.65) | IGF1RALOX15ACHEESR1ADRA2A | |
| SCHEMBL21963890 | 0.87 | ESR1 (0.65) | IGF1RALOX15ACHEESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12163043-B2 | Curable composition comprising polysiloxane polyalkyleneglycol brush copolymers | HENKEL AG & CO. KGAA (DE) | 2024-12-10 | — | — | US | disclosed |
| EP-3784718-B1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHERPOLYSILOXANE BLOCK COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2024-06-26 | — | — | EP | disclosed |
| CN-114096590-B | UV and/or thermally curable silicone-based materials and formulations | 汉高股份有限及两合公司 | 2024-04-19 | — | — | CN | disclosed |
| EP-3663372-B1 | CURABLE COMPOSITION COMPRISING POLYSILOXANE POLYALKYLENEGLYCOL BRUSH COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2024-03-13 | — | — | EP | disclosed |
| US-20220411634-A1 | SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY | HENKEL AG & CO. KGAA (DE) | 2022-12-29 | — | — | US | disclosed |
| EP-4108726-A1 | SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY | Henkel AG & Co. KGaA (DE) | 2022-12-28 | — | — | EP | disclosed |
| US-11326027-B2 | Process for the preparation of hydroxyl-functionalized polysiloxanes | HENKEL AG & CO. KGAA (DE) | 2022-05-10 | — | — | US | disclosed |
| CN-114096590-A | UV and/or thermally curable silicone-based materials and formulations | 汉高知识产权控股有限责任公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-3953412-A1 | UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS | Henkel IP & Holding GmbH (DE) | 2022-02-16 | — | — | EP | disclosed |
| US-20220025180-A1 | UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS | HENKEL AG & CO. KGAA (DE) | 2022-01-27 | — | — | US | disclosed |
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0321174-B1 | Process for preparing aminopropyl silanes | TONEN CORP (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-4921988-A | RHODIUM CATALYST, BASE, ALLYLAMINE | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0321174-A2 | Process for preparing aminopropyl silanes | Tonen Corporation (JP) | 1989-06-21 | — | — | EP | disclosed |
| US-4834905-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |
| US-4627933-A | ESTERS, ETHERS, NITRICES, HALIDES, OR HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0104327-A2 | Use of cyclic derivatives as components of liquid cristals | MERCK PATENT GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11326027-B2 | Process for the preparation of hydroxyl-functionalized polysiloxanes | C9, HACL2, ADH1C | IGF1R 965/4885ALOX15 1048/4885CYP1A2 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.