SCHEMBL6546792

SCHEMBL6546792

C/C=C\c1cccc(C)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.40
PTGS2 P35354 3/20 0.40
FABP4 P15090 1/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
BRD4 O60885 2/20 0.37
BRD2 P25440 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RPA1 P27694 1/20 0.36
MCL1 Q07820 1/20 0.36
FGFR1 P11362 1/20 0.36
FGFR2 P21802 1/20 0.36
FGFR4 P22455 1/20 0.36
FGFR3 P22607 1/20 0.36
RET P07949 1/20 0.36
AKT2 P31751 2/20 0.35
MYC P01106 1/20 0.35
TDO2 P48775 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546806 1.00 PTGS1 (0.40) PTGS1PTGS2FABP4TSHRALDH1A1
SCHEMBL6546478 0.81 PTGS1 (0.38) PTGS1PTGS2TSHRBRD4BRD2
SCHEMBL6546082 0.81 PTGS1 (0.38) PTGS1PTGS2FABP4BRD4BRD2
SCHEMBL6547166 0.79 PTGER1 (0.38) PTGS1PTGS2FABP4TSHRALDH1A1
SCHEMBL6546609 0.79 PDE4A (0.38) PTGS1PTGS2FABP4TSHRALDH1A1
SCHEMBL672547 0.78 ALDH1A1 (0.54) PTGS2TSHRALDH1A1NPC1RAB9A
SCHEMBL29443143 0.78 ALDH1A1 (0.54) PTGS2TSHRALDH1A1NPC1RAB9A
SCHEMBL2308209 0.78 ALDH1A1 (0.54) PTGS2TSHRALDH1A1NPC1RAB9A
SCHEMBL672548 0.78 ALDH1A1 (0.54) PTGS2TSHRALDH1A1NPC1RAB9A
SCHEMBL29444192 0.78 ALDH1A1 (0.54) PTGS2TSHRALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed