SCHEMBL6546945

SCHEMBL6546945

Cc1ccc(C(C)c2ccccc2C)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASR P41180 1/20 0.51
ESR1 P03372 1/20 0.43
LMNA P02545 3/20 0.41
TRPA1 O75762 1/20 0.41
CHRM1 P11229 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1A P35348 1/20 0.41
HTR2B P41595 1/20 0.41
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
CYP2A6 P11509 2/20 0.37
TP53 P04637 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 2/20 0.36
ELANE P08246 1/20 0.36
TSHR P16473 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546836 0.89 CASR (0.50) CASRLMNATRPA1CHRM1SLC6A2
SCHEMBL11881991 0.85 LMNA (0.48) CASRESR1LMNATRPA1CHRM1
SCHEMBL5605959 0.85 CASR (0.47) CASRESR1LMNATRPA1CHRM1
SCHEMBL146510 0.84 ESR1 (0.56) ESR1SLC6A2ADRA1ATDP1CYP2A6
SCHEMBL6547628 0.82 CASR (0.44) CASRLMNATRPA1CHRM1SLC6A2
SCHEMBL28682080 0.82 TYR (0.50) CASRESR1LMNATRPA1CHRM1
SCHEMBL439493 0.82 TYR (0.50) CASRESR1LMNATRPA1CHRM1
SCHEMBL29486481 0.82 TYR (0.50) CASRESR1LMNATRPA1CHRM1
Diphenylmethane SCHEMBL10899649 0.81 CASR (0.47) CASRGPR55TSHR
SCHEMBL11878851 0.81 LMNA (0.46) CASRESR1LMNATRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0015758-B1 PROCESS FOR PRODUCING STYRENES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-05-05 EP disclosed
EP-0015758-A1 Process for producing styrenes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-09-17 EP disclosed