SCHEMBL6546965

SCHEMBL6546965

CCc1ccc(C=Cc2ccc(C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.60
PTGS2 P35354 3/20 0.60
ALOX5 P09917 2/20 0.60
NFE2L2 Q16236 5/20 0.54
TUBB1 Q9H4B7 2/20 0.52
RELA Q04206 1/20 0.50
CA1 P00915 1/20 0.45
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29086916 1.00 PTGS1 (0.60) PTGS1PTGS2ALOX5NFE2L2TUBB1
SCHEMBL28779438 1.00 PTGS1 (0.60) PTGS1PTGS2ALOX5NFE2L2TUBB1
SCHEMBL4239993 0.91 ALOX5 (0.52) PTGS1PTGS2ALOX5NFE2L2TUBB1
SCHEMBL16853122 0.90 ALOX5 (0.63) PTGS1PTGS2ALOX5TUBB1CYP2A6
SCHEMBL6546261 0.90 ALOX5 (0.63) PTGS1PTGS2ALOX5TUBB1CYP2A6
SCHEMBL9026437 0.90 ALOX5 (0.63) PTGS1PTGS2ALOX5TUBB1CYP2A6
SCHEMBL9026432 0.90 ALOX5 (0.63) PTGS1PTGS2ALOX5TUBB1CYP2A6
SCHEMBL14847302 0.90 ALOX5 (0.51) PTGS1PTGS2ALOX5NFE2L2TUBB1
SCHEMBL14295899 0.90 ALOX5 (0.51) PTGS1PTGS2ALOX5NFE2L2TUBB1
SCHEMBL4403035 0.90 ALOX5 (0.51) PTGS1PTGS2ALOX5NFE2L2TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114713283-A Cobalt nanoparticle efficient selective catalytic system and method for reducing alkyne to generate (Z) -olefin by using same 沈阳药科大学 2022-07-08 CN disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed