Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546854 | 1.00 | ESR1 (0.57) | ESR1ESR2TSHRMAPK1ATM | |
| SCHEMBL6547203 | 0.92 | ESR1 (0.65) | ESR1ESR2TSHRACHEGRIA4 | |
| SCHEMBL6546198 | 0.84 | ESR1 (0.57) | ESR1ESR2TSHRMAPK1ATM | |
| SCHEMBL1954002 | 0.82 | ESR1 (0.85) | ESR1ESR2MAPK1L3MBTL1ACHE | |
| SCHEMBL21699675 | 0.82 | ESR1 (0.55) | ESR1ESR2TSHRMAPK1ATM | |
| SCHEMBL1841040 | 0.82 | ESR1 (0.85) | ESR1ESR2MAPK1L3MBTL1ACHE | |
| SCHEMBL2844467 | 0.82 | ESR1 (0.55) | ESR1ESR2L3MBTL1ACHESMN1; SMN2 | |
| SCHEMBL1842701 | 0.82 | ESR1 (0.85) | ESR1ESR2MAPK1TDP1L3MBTL1 | |
| SCHEMBL1952940 | 0.82 | ESR1 (0.85) | ESR1ESR2MAPK1TDP1L3MBTL1 | |
| SCHEMBL5313594 | 0.82 | ESR1 (0.53) | ESR1ESR2ACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |