SCHEMBL6547203

SCHEMBL6547203

Cc1ccc(CC(C)c2ccc(C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.65
ESR2 Q92731 1/20 0.65
ACHE P22303 2/20 0.47
STAT3 P40763 1/20 0.43
IDO1 P14902 1/20 0.42
GRIA4 P48058 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
BCHE P06276 1/20 0.40
PTGS1 P23219 3/20 0.39
PTGS2 P35354 3/20 0.39
LMNA P02545 2/20 0.39
CYP2C9 P11712 2/20 0.39
AKR1C3 P42330 2/20 0.39
CXCR1 P25024 2/20 0.39
CXCR2 P25025 2/20 0.39
ALB P02768 1/20 0.39
ALOX5 P09917 1/20 0.39
RARB P10826 1/20 0.39
ADRB3 P13945 1/20 0.39
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546854 0.92 ESR1 (0.57) ESR1ESR2ACHESTAT3IDO1
SCHEMBL6546983 0.92 ESR1 (0.57) ESR1ESR2ACHESTAT3IDO1
SCHEMBL1954002 0.90 ESR1 (0.85) ESR1ESR2ACHECYP2C9BLM
SCHEMBL21699675 0.90 ESR1 (0.55) ESR1ESR2ACHESTAT3IDO1
SCHEMBL1841040 0.90 ESR1 (0.85) ESR1ESR2ACHECYP2C9BLM
SCHEMBL2844467 0.90 ESR1 (0.55) ESR1ESR2ACHESMN1; SMN2BCHE
SCHEMBL5313594 0.89 ESR1 (0.53) ESR1ESR2ACHESMN1; SMN2CYP2A6
SCHEMBL2844291 0.89 ESR1 (0.53) ESR1ESR2SMN1; SMN2AKR1C3CYP2A6
SCHEMBL15070045 0.88 ESR1 (0.53) ESR1ESR2ACHESTAT3CYP1A2
Ammonia Solution, Strong SCHEMBL5308343 0.87 ESR1 (0.52) ESR1ESR2ACHESMN1; SMN2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0206699-B1 SOLVENT FOR CHROMOGENIC DYE-PRECURSORS FOR PRESSURE-SENSITIVE RECORDING PAPERS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-04-11 EP disclosed
US-4786630-A MIXTURE OF 1-TOLYL-2-PHENYLPROPANE AND 1,2-DITOLYLETHANE KUREHA KAGAKU KOGYO KABUSHIKI KAISHI (JP) 1988-11-22 US disclosed
US-4737189-A MIXED REACTION PRODUCT OF COUPLING ETHYLBENZENE AND XYLENE Kawaguti & Partners (JP) 1988-04-12 US disclosed
EP-0206699-A1 Solvent for chromogenic dye-precursors for pressure-sensitive recording papers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed