SCHEMBL6547030

SCHEMBL6547030

COC(=O)CCC(=O)OC=O

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.65
ALDH1A1 P00352 5/20 0.47
LMNA P02545 4/20 0.47
KDM4E B2RXH2 2/20 0.46
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HTT P42858 2/20 0.45
MAPT P10636 1/20 0.45
MEN1 O00255 1/20 0.43
CA12 O43570 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
RECQL P46063 1/20 0.37
POLB P06746 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11882292 0.98 TSHR (0.62) TSHRALDH1A1LMNAKDM4EKMT2A
SCHEMBL1436576 0.87 TSHR (0.40) TSHRALDH1A1LMNA
SCHEMBL9490456 0.82 GAA (0.48) TSHRALDH1A1LMNAKDM4EKMT2A
Dimethyl Succinate SCHEMBL28185979 0.81 TSHR (0.87) TSHRALDH1A1LMNAKDM4EKMT2A
Dimethyl Succinate SCHEMBL28054469 0.81 TSHR (1.00) TSHRALDH1A1LMNAKDM4EKMT2A
Dimethyl Succinate SCHEMBL10213 0.81 TSHR (1.00) TSHRALDH1A1LMNAKDM4EKMT2A
SCHEMBL16114768 0.80 ALDH1A1 (0.50) TSHRALDH1A1LMNAMAPTMGAM
SCHEMBL11685079 0.80 GAA (0.46) TSHRALDH1A1LMNAKDM4EKMT2A
SCHEMBL9439793 0.78 ALDH1A1 (0.48) TSHRALDH1A1LMNAMAPTMGAM
Water SCHEMBL11684203 0.78 GAA (0.44) TSHRALDH1A1LMNAKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10066868-A None JP disclosed
WO-2023177701-A1 AQUEOUS HARD SURFACE CLEANING FORMULATION ROHM AND HAAS COMPANY (US) 2023-09-21 WO disclosed
EP-3833731-A1 COMPOSITIONS COMPRISING A LIPOLYTIC ENZYME VARIANT AND METHODS OF USE THEREOF Danisco US Inc. (US) 2021-06-16 EP disclosed
WO-2020046613-A1 COMPOSITIONS COMPRISING A LIPOLYTIC ENZYME VARIANT AND METHODS OF USE THEREOF DANISCO US INC (US) 2020-03-05 WO disclosed
CN-104302648-B The crystal form of succinate 诺华股份有限公司 2016-11-23 CN disclosed
EP-1432759-A1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-06-30 EP disclosed
EP-1119601-B1 LIQUID DETERGENT KAO CORP (JP) 2004-01-28 EP disclosed
WO-2003020819-A1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2003-03-13 WO disclosed
US-6387867-B1 REMOVING OILS; COSMETIC CLEANING COMPOUND KAO CORPORATION (JP) 2002-05-14 US disclosed
EP-1119601-A1 LIQUID DETERGENT Kao Corporation (JP) 2001-08-01 EP disclosed
US-4988363-A WASHING FABRICS USING ORGANIC PEROXYACIDS AS BLEACHES; CONTROLLING PH LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-01-29 US disclosed
EP-0290081-B1 IMPROVED DETERGENT BLEACH COMPOSITION AND METHOD OF CLEANING FABRICS UNILEVER N.V. (NL) 1990-10-31 EP disclosed
EP-0178006-B1 LIQUID DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 1990-09-12 EP disclosed
EP-0290081-A1 Improved detergent bleach composition and method of cleaning fabrics UNILEVER N.V. (NL) 1988-11-09 EP disclosed
EP-0237111-A2 Detergent bleach composition, bleaching compositions and bleach activators UNILEVER N.V. (NL) 1987-09-16 EP disclosed
EP-0178006-A2 Liquid detergent compositions UNILEVER N.V. (NL) 1986-04-16 EP disclosed
US-4539144-A Dishwashing compositions with an anti-filming polymer LEVER BROTHERS COMPANY (US) 1985-09-03 US disclosed
EP-0082564-A2 Dishwashing composition UNILEVER N.V. (NL) 1983-06-29 EP disclosed
US-3914297-A Carboxy methyloxy succinates LEVER BROTHERS LTD 1975-10-21 US disclosed
US-3894081-A Recovery of pentahydrate trisodium salt of carboxymethoxy succinic acid from aqueous solution ETHYL CORP 1975-07-08 US disclosed