SCHEMBL6547249

SCHEMBL6547249

O=CCCOCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35
TDP1 Q9NUW8 4/20 0.33
KDM4E B2RXH2 3/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
POLB P06746 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TTR P02766 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32
PLAU P00749 1/20 0.32
ORAI1 Q96D31 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548361 0.94 HTT (0.34) HTTPLAU
SCHEMBL6549182 0.94 HTT (0.34) HTTTDP1KDM4EKMT2AMEN1
SCHEMBL6549096 0.92 S1PR2 (0.34) HTTKMT2AMEN1PLAU
SCHEMBL6549083 0.92 S1PR2 (0.34) HTTKMT2AMEN1PLAU
SCHEMBL6548008 0.92 HTT (0.38) HTTPLAU
SCHEMBL6548577 0.89 HTT (0.36) HTTTDP1KDM4EKMT2AMEN1
SCHEMBL6547316 0.88 HTT (0.37) HTTTDP1KDM4EKMT2AMEN1
SCHEMBL6548273 0.86 HTT (0.36) HTTTDP1KDM4EKMT2AMEN1
SCHEMBL7632172 0.86 HTT (0.36) HTTTDP1KDM4EKMT2AL3MBTL1
SCHEMBL6549739 0.85 HTT (0.35) HTTTDP1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HTT 4052/4885TDP1 2528/4885KDM4E 1500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.