SCHEMBL6547258

SCHEMBL6547258

CCCCC(C)(c1ccccc1O)c1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
HSP90AA1 P07900 3/20 0.40
HSP90AB1 P08238 3/20 0.40
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
NAAA Q02083 1/20 0.36
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3152828 0.94 ALDH1A1 (0.50) TSHRALDH1A1TDP1ESR1ESR2
SCHEMBL8519170 0.93 ALDH1A1 (0.48) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL18223904 0.93 ALDH1A1 (0.48) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL9330085 0.88 ALDH1A1 (0.56) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL1581665 0.88 ALDH1A1 (0.56) TSHRALDH1A1TDP1ESR1ESR2
SCHEMBL887818 0.85 TSHR (0.52) TSHRALDH1A1TDP1ESR1ESR2
SCHEMBL980190 0.85 TSHR (0.52) TSHRALDH1A1TDP1ESR1ESR2
SCHEMBL27706717 0.83 CNR1 (0.43) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL981802 0.82 TSHR (0.48) TSHRALDH1A1TDP1ESR1ESR2
SCHEMBL8617659 0.81 TSHR (0.47) TSHRALDH1A1TDP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556308-B1 OXYSULFONYL UREA ACAT INHIBITORS WARNER LAMBERT CO (US) 1995-02-01 EP claimed
EP-0626409-B1 Method for making aromatic polycarbonates GEN ELECTRIC (US) 2004-01-21 EP disclosed
US-5804525-A BINARY CATALYST OF TERTIARY ORGANIC AMINE AND PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1998-09-08 US disclosed
US-5744416-A USING TERTIARY AMINE OR PHOSPHONIUM CATALYST FOR INTERFACIAL POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 1998-04-28 US disclosed
US-5519105-A CONDENSATION POLYMERIZATION IN THE PRESENCE OF PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1996-05-21 US disclosed
US-5510449-A Catalyst system for polycarbonate manufacture GENERAL ELECTRIC COMPANY (US) 1996-04-23 US disclosed
EP-0682056-A2 Catalyst system for polycarbonate manufacture GENERAL ELECTRIC COMPANY (US) 1995-11-15 EP disclosed
EP-0682055-A2 Binary catalyst for making aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1995-11-15 EP disclosed
EP-0666277-A2 Method for making aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1995-08-09 EP disclosed
EP-0353776-B1 Polycarbonate composition TEIJIN CHEMICALS LTD (JP) 1995-01-18 EP disclosed
EP-0626409-A2 Method for making aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1994-11-30 EP disclosed
US-4965303-A DISCOLORATION INHIBITION TEIJIN CHEMICALS, LTD. (JP) 1990-10-23 US disclosed
EP-0353776-A2 Polycarbonate composition Teijin Chemicals, Ltd. (JP) 1990-02-07 EP disclosed