Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.52 |
| ▸ | PIM1 | P11309 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 3/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | CDK9 | P50750 | 3/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.52 |
| ▸ | MELK | Q14680 | 3/20 | 0.52 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 5/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698720 | 0.83 | CDC7 (0.58) | CDC7DAPK3PIM1CDK2FLT3 | |
| SCHEMBL10879147 | 0.82 | AKR1C3 (0.44) | CDC7DAPK3PIM1CDK2FLT3 | |
| SCHEMBL7712957 | 0.78 | ALDH1A1 (0.39) | CDC7DAPK3PIM1CDK2FLT3 | |
| SCHEMBL7712964 | 0.78 | KDM4E (0.42) | CDC7DAPK3PIM1CDK2FLT3 | |
| SCHEMBL5686015 | 0.78 | AURKA (0.66) | CDC7DAPK3PIM1CDK2FLT3 | |
| SCHEMBL29603638 | 0.78 | AURKA (0.66) | CDC7DAPK3PIM1CDK2FLT3 | |
| SCHEMBL8092217 | 0.76 | NPC1 (0.46) | CDK2CDK5AURKAALDH1A1MAPT | |
| SCHEMBL10910707 | 0.76 | TSHR (0.53) | FLT3AURKAKDM4EALDH1A1MAPT | |
| SCHEMBL8087455 | 0.75 | GAA (0.41) | POLBGAAPTGS1PTGS2 | |
| SCHEMBL4651692 | 0.75 | AURKA (0.45) | PIM1CDK2FLT3GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962500-B1 | Water soluble monoazo compounds, process for their preparation and their use as dyestuffs | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-5831039-A | Fiber reactive polyazo dyes containing two urea groups | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0872523-A2 | Fiber-reactive azo dyes, process for their preparation and the use thereof | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1998-10-21 | — | — | EP | disclosed |