Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 13/20 | 0.35 |
| ▸ | PPARG | P37231 | 12/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547501 | 0.99 | NPC1 (0.39) | NPC1RAB9APSEN1PSEN2APH1B | |
| SCHEMBL6547665 | 0.98 | NPC1 (0.38) | NPC1RAB9APSEN1PSEN2APH1B | |
| SCHEMBL6547702 | 0.94 | NPC1 (0.39) | NPC1RAB9APSEN1PSEN2APH1B | |
| SCHEMBL6547172 | 0.93 | NPC1 (0.39) | NPC1RAB9APSEN1PSEN2APH1B | |
| SCHEMBL6548322 | 0.92 | NPC1 (0.37) | NPC1RAB9APSEN1PSEN2APH1B | |
| SCHEMBL6547596 | 0.91 | PPARA (0.45) | NPC1RAB9APPARAPPARGHTT | |
| SCHEMBL6550117 | 0.90 | PPARA (0.44) | NPC1RAB9APPARAPPARGHTT | |
| SCHEMBL6548115 | 0.89 | PPARA (0.42) | NPC1RAB9APPARAPPARGHTT | |
| SCHEMBL6549954 | 0.89 | NPC1 (0.39) | NPC1RAB9APSEN1PSEN2APH1B | |
| SCHEMBL6548174 | 0.88 | PPARA (0.46) | PPARAPPARGHTTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975586-B1 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6448444-B2 | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-09-10 | — | — | US | disclosed |
| US-6437184-B1 | INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-08-20 | — | — | US | disclosed |