SCHEMBL6547702

SCHEMBL6547702

CCc1cc(OCC=C(Cl)Cl)cc(C)c1OCCCCON=C(C)c1ccc(Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PPARA Q07869 14/20 0.38
PPARG P37231 13/20 0.38
SLC6A4 P31645 1/20 0.36
PSEN1 P49768 3/20 0.34
PSEN2 P49810 3/20 0.34
APH1B Q8WW43 3/20 0.34
NCSTN Q92542 3/20 0.34
APH1A Q96BI3 3/20 0.34
PSENEN Q9NZ42 3/20 0.34
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547172 0.99 NPC1 (0.39) NPC1RAB9APPARAPPARGSLC6A4
SCHEMBL6548322 0.98 NPC1 (0.37) NPC1RAB9APPARAPPARGSLC6A4
SCHEMBL6547852 0.94 NPC1 (0.40) NPC1RAB9APPARAPPARGSLC6A4
SCHEMBL6547501 0.93 NPC1 (0.39) NPC1RAB9APPARAPPARGSLC6A4
SCHEMBL6547665 0.92 NPC1 (0.38) NPC1RAB9APPARAPPARGSLC6A4
SCHEMBL6547663 0.91 PPARA (0.47) NPC1RAB9APPARAPPARGHTT
SCHEMBL6548862 0.91 PPARA (0.46) NPC1RAB9APPARAPPARGHTT
SCHEMBL6548453 0.90 PPARA (0.44) NPC1RAB9APPARAPPARGHTT
SCHEMBL6547280 0.89 SLC6A4 (0.38) NPC1RAB9APPARAPPARGSLC6A4
SCHEMBL6548176 0.89 PPARA (0.48) PPARAPPARGSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 NPC1 1404/4885RAB9A 2309/4885PPARA 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.