Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789641 | 0.81 | POLB (0.63) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL6548135 | 0.79 | POLB (0.59) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL862980 | 0.76 | POLB (0.73) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL4608475 | 0.76 | LMNA (0.67) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL2007287 | 0.75 | POLB (0.70) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL7331346 | 0.75 | POLB (0.70) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL30817867 | 0.75 | MAPK1 (0.70) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL13290951 | 0.75 | POLB (0.70) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL10497757 | 0.75 | POLB (0.70) | POLBTSHRMAPK1LMNAHTT | |
| SCHEMBL6038065 | 0.75 | POLB (0.70) | POLBTSHRMAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | claimed |
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | claimed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | claimed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | claimed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | claimed |
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | disclosed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | disclosed |