SCHEMBL6548571

SCHEMBL6548571

ClC(Cl)=CCOc1cc(Cl)c(OCCCO/N=C/c2ccccc2)c(Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
UNG P13051 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
PPARG P37231 4/20 0.35
PPARA Q07869 4/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
HPGD P15428 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
FAAH O00519 3/20 0.33
ACHE P22303 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548576 1.00 UNG (0.37) UNGMEN1KMT2APPARGPPARA
SCHEMBL6547281 0.98 UNG (0.39) UNGMEN1KMT2APPARGPPARA
SCHEMBL6547276 0.98 UNG (0.39) UNGMEN1KMT2APPARGPPARA
SCHEMBL6549759 0.97 UNG (0.38) UNGMEN1KMT2APPARGPPARA
SCHEMBL6549756 0.97 UNG (0.38) UNGMEN1KMT2APPARGPPARA
SCHEMBL6548207 0.93 PPARG (0.35) UNGMEN1KMT2APPARGPPARA
SCHEMBL6548204 0.93 PPARG (0.35) UNGMEN1KMT2APPARGPPARA
SCHEMBL6549171 0.91 KMT2A (0.41) UNGMEN1KMT2APPARGPPARA
SCHEMBL6549175 0.91 KMT2A (0.41) UNGMEN1KMT2APPARGPPARA
SCHEMBL6549482 0.91 UNG (0.36) UNGMEN1KMT2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 UNG 3162/4885MEN1 4425/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.