SCHEMBL6548708

SCHEMBL6548708

O=[N+]([O-])c1ccc(ON=CCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)c([N+](=O)[O-])c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.37
LMNA P02545 6/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
HPGD P15428 3/20 0.37
KMT2A Q03164 7/20 0.35
MEN1 O00255 6/20 0.35
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 3/20 0.35
ALDH1A1 P00352 4/20 0.34
NPC1 O15118 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MANBA O00462 1/20 0.34
MTOR P42345 1/20 0.33
HSPB1 P04792 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548704 1.00 MAPT (0.37) MAPTLMNASMN1; SMN2HPGDKMT2A
SCHEMBL8632767 0.79 MEN1 (0.48) MAPTLMNAHPGDKMT2AMEN1
SCHEMBL6547717 0.77 PTGIR (0.34) MAPTHPGDHTT
SCHEMBL6547713 0.77 PTGIR (0.34) MAPTHPGDHTT
SCHEMBL6548315 0.76 GAA (0.41) MAPTLMNASMN1; SMN2HPGDKMT2A
SCHEMBL6549274 0.76 HDAC1 (0.39) MAPTLMNASMN1; SMN2HPGDKMT2A
SCHEMBL6549277 0.76 HDAC1 (0.39) MAPTLMNASMN1; SMN2HPGDKMT2A
SCHEMBL6548393 0.75 HTT (0.31) HTT
SCHEMBL6548388 0.75 HTT (0.31) HTT
SCHEMBL8636378 0.75 PDE7A (0.49) MAPTLMNASMN1; SMN2HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MAPT 4623/4885LMNA 3205/4885SMN1; SMN2 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.