SCHEMBL6548759

SCHEMBL6548759

COCNc1cccc(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.40
KDM4E B2RXH2 2/20 0.38
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
GAA P10253 3/20 0.35
LMNA P02545 2/20 0.35
PSIP1 O75475 1/20 0.34
HPGD P15428 1/20 0.33
BCDIN3D Q7Z5W3 1/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CSF1R P07333 1/20 0.32
CHRM3 P20309 1/20 0.32
MAPK1 P28482 1/20 0.32
ALPL P05186 1/20 0.32
ALPI P09923 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28907686 0.84 L3MBTL1 (0.54) L3MBTL1RAB9ANPC1GAALMNA
SCHEMBL6085317 0.78 GAA (0.42) L3MBTL1KDM4ERAB9ANPC1GAA
SCHEMBL6549660 0.73 KDM4E (0.39) L3MBTL1KDM4EGAAPSIP1ALDH1A1
SCHEMBL11554492 0.71 KDM4E (0.41) L3MBTL1KDM4ERAB9ANPC1PSIP1
SCHEMBL1547937 0.70 MAPT (0.39) L3MBTL1KDM4ERAB9ANPC1GAA
SCHEMBL14318813 0.69 MAPT (0.61) KDM4ERAB9ANPC1GAALMNA
SCHEMBL31544492 0.69 MAPT (0.61) KDM4ERAB9ANPC1GAALMNA
SCHEMBL21662566 0.69 KDM4E (0.42) L3MBTL1KDM4ERAB9AHPGDALDH1A1
SCHEMBL11511266 0.69 HSD17B10 (0.53) L3MBTL1KDM4EGAALMNAHPGD
SCHEMBL28860071 0.69 L3MBTL1 (0.51) L3MBTL1KDM4EGAALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1366026-B1 PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed