Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610485 | 1.00 | EPHX1 (0.42) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL5497437 | 0.98 | EPHX1 (0.39) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL27280420 | 0.94 | EPHX1 (0.35) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL30313871 | 0.90 | MEN1 (0.31) | CYP19A1 | |
| SCHEMBL24147621 | 0.85 | EPHX1 (0.40) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL16731836 | 0.84 | EPHX1 (0.44) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| Cilexetil SCHEMBL3483374 | 0.84 | EPHX1 (0.44) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL1240114 | 0.82 | EPHX1 (0.43) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL1240113 | 0.82 | EPHX1 (0.43) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL3483069 | 0.82 | EPHX1 (0.41) | EPHX1CYP19A1NAAAHTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118476590-A | Anhydrous deoxidizing agent | 上海樱琦干燥剂有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-117907463-A | Method for measuring content of 1-chloroethyl cyclohexyl carbonate in candesartan cilexetil and application | 南京明捷生物医药检测有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117777110-A | Preparation method of candesartan cilexetil | 山西皇城相府药业股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117069704-A | Candesartan cilexetil and preparation method thereof | 安徽美诺华药物化学有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-115322175-A | Synthesis process of candesartan | 安徽美诺华药物化学有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-111747902-B | Candesartan cilexetil intermediate and application thereof | 浙江天宇药业股份有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-110501449-B | Method for detecting toxic impurities of candesartan cilexetil group | 迪嘉药业集团有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-107089972-B | Preparation method of candesartan cilexetil | 浙江华海药业股份有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-212523060-U | Distillation recovery device used in preparation of chloroethyl cyclohexyl carbonate | 金溪斯普瑞药业有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-111773754-A | Distillation recovery device used in preparation of chloroethyl cyclohexyl carbonate | 金溪斯普瑞药业有限公司 | 2020-10-16 | — | — | CN | claimed |
| WO-2007094015-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL | MATRIX LABORATORIES LTD (IN) | 2007-08-23 | — | — | WO | claimed |
| WO-2007074399-A2 | PROCESS FOR THE PREPARATION OF TETRAZOLYL COMPOUNDS | MEDICHEM, S.A. (US) | 2007-07-05 | — | — | WO | claimed |
| EP-1778650-A1 | PROCESS FOR PREPARING CANDESARTAN CILEXETIL | Dr. Reddy's Laboratories Ltd. (IN) | 2007-05-02 | — | — | EP | claimed |
| EP-1685126-B1 | PREPARATION OF CANDESARTAN CILEXETIL | TEVA PHARMA (IL) | 2007-03-21 | — | — | EP | claimed |
| CN-1902192-A | Preparation of candesartan cilexetil | TEVA PHARMA (IL) | 2007-01-24 | — | — | CN | claimed |
| US-7098342-B2 | Preparation of candesartan cilexetil | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-08-29 | — | — | US | claimed |
| EP-1685126-A2 | PREPARATION OF CANDESARTAN CILEXETIL | Teva Pharmaceutical Industries Limited (IL) | 2006-08-02 | — | — | EP | claimed |
| WO-2006015134-A1 | PROCESS FOR PREPARING CANDESARTAN CILEXETIL | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-02-09 | — | — | WO | claimed |
| US-20050131037-A1 | Preparation of candesartan cilexetil | TEVA PHARMACEUTICALS USA, INC. | 2005-06-16 | — | — | US | claimed |
| WO-2005037821-A2 | PREPARATION OF CANDESARTAN CILEXETIL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-04-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131037-A1 | Preparation of candesartan cilexetil | REN, ACE, AGT | EPHX1 1397/4885CYP19A1 3493/4885NAAA 3134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.