SCHEMBL6548864

SCHEMBL6548864

CCCCCCCCCCCOC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.50
GBA1 P04062 3/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 1/20 0.41
EPHX2 P34913 2/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
SIGMAR1 Q99720 1/20 0.37
RECQL P46063 2/20 0.36
CES2 O00748 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743879 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL6549442 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL7776934 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL732227 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL8743876 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL731632 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL8743886 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL1898488 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL22709126 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1
SCHEMBL10928958 1.00 NAAA (0.50) NAAAGBA1NPC1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018884-B1 PROCESS FOR THE PREPARATION OF TRIS(ETHER AMINES) AND SO OBTAINED TRIS(ETHER AMINES) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-11-04 EP claimed
EP-0018884-A1 Process for the preparation of tris(ether amines) and so obtained tris(ether amines) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1980-11-12 EP claimed
EP-1129065-B1 METHOD FOR PREPARING TRIS(ETHER-AMINE) RHODIA CHIMIE SA (FR) 2004-01-21 EP disclosed
EP-1129065-A1 METHOD FOR PREPARING TRIS(ETHER-AMINE) RHODIA CHIMIE (FR) 2001-09-05 EP disclosed
WO-2000027796-A1 METHOD FOR PREPARING TRIS(ETHER-AMINE) RHODIA CHIMIE (FR) 2000-05-18 WO disclosed
EP-0790824-A1 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE Roche Diagnostics GmbH (DE) 1997-08-27 EP disclosed
WO-1996015784-A2 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE BOEHRINGER MANNHEIM GMBH (DE) 1996-05-30 WO disclosed
EP-0018884-B1 PROCESS FOR THE PREPARATION OF TRIS(ETHER AMINES) AND SO OBTAINED TRIS(ETHER AMINES) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-11-04 EP disclosed
EP-0018884-A1 Process for the preparation of tris(ether amines) and so obtained tris(ether amines) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1980-11-12 EP disclosed