SCHEMBL6549146

SCHEMBL6549146

CC(=NOCC=C(Br)Br)c1ccc(OCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
FURIN P09958 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GAA P10253 1/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547965 0.98 HTT (0.36) HTTFURINSMN1; SMN2
SCHEMBL6547887 0.95 HTT (0.39) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6548442 0.93 HTT (0.39) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6548597 0.90 HTT (0.39) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6549633 0.89 HTT (0.38) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6548310 0.89 HTT (0.38) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6548389 0.88 HTT (0.37) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6548681 0.88 HTT (0.39) HTTFURINSMN1; SMN2L3MBTL1GAA
SCHEMBL6548268 0.87 HTT (0.39) HTTFURINL3MBTL1GAAPPARG
SCHEMBL6547864 0.87 HTT (0.39) HTTFURINSMN1; SMN2L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 HTT 4052/4885FURIN 3892/4885SMN1; SMN2 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.