SCHEMBL6549290

SCHEMBL6549290

Cc1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCCCON=Cc1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.38
L3MBTL1 Q9Y468 4/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 3/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
RECQL P46063 1/20 0.32
MAOB P27338 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 2/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549285 1.00 MAPT (0.38) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6549543 0.99 MAPT (0.38) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6549536 0.99 MAPT (0.38) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6549160 0.97 MAPT (0.38) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6549155 0.97 MAPT (0.38) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6548830 0.93 KMT2A (0.41) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6548824 0.93 KMT2A (0.41) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL6548317 0.92 HDAC1 (0.37) L3MBTL1MEN1KMT2AKDM4EHDAC1
SCHEMBL6548311 0.92 HDAC1 (0.37) L3MBTL1MEN1KMT2AKDM4EHDAC1
SCHEMBL6548303 0.92 KMT2A (0.41) MAPTL3MBTL1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MAPT 4623/4885L3MBTL1 876/4885MEN1 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.