Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549315 | 1.00 | ALDH1A1 (0.38) | ALDH1A1ALOX15GAAHTTTDP1 | |
| SCHEMBL5174066 | 0.90 | CYP3A4 (0.35) | ALDH1A1ALOX15GAAHTTTDP1 | |
| SCHEMBL5417586 | 0.90 | CYP3A4 (0.35) | ALDH1A1ALOX15GAAHTTTDP1 | |
| SCHEMBL6548295 | 0.84 | CYP1A2 (0.35) | ALDH1A1CASP1MAPT | |
| SCHEMBL6548291 | 0.84 | CYP1A2 (0.35) | ALDH1A1CASP1MAPT | |
| Hydrochloric Acid SCHEMBL6748189 | 0.82 | CYP1A2 (0.35) | ALDH1A1CASP1MAPT | |
| Hydrochloric Acid SCHEMBL6748187 | 0.82 | CYP1A2 (0.35) | ALDH1A1CASP1MAPT | |
| SCHEMBL6549859 | 0.82 | CYP3A4 (0.38) | ALDH1A1ALOX15GAAHTTTDP1 | |
| SCHEMBL6550255 | 0.82 | CYP3A4 (0.38) | ALDH1A1ALOX15GAAHTTTDP1 | |
| SCHEMBL4602419 | 0.82 | KDM4E (0.38) | ALDH1A1ALOX15GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699296-B2 | Mixture containing phenylenediamine developer | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | claimed |
| EP-1183227-B1 | P-DIAMINOBENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-04 | — | — | EP | claimed |
| US-20030145764-A1 | P-diaminobenzene derivatives and dyes containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-08-07 | — | — | US | claimed |
| US-6699296-B2 | Mixture containing phenylenediamine developer | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030145764-A1 | P-diaminobenzene derivatives and dyes containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-08-07 | — | — | US | disclosed |