SCHEMBL6549403

SCHEMBL6549403

O=C1N(Cc2ccccc2)C(=O)C2(CCCCC2)NC12CCCCC2

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.77
ALDH1A1 P00352 6/20 0.56
ELANE P08246 2/20 0.53
SMN1; SMN2 Q16637 4/20 0.52
LMNA P02545 4/20 0.52
MAPK1 P28482 1/20 0.52
MAPT P10636 1/20 0.51
MEN1 O00255 1/20 0.51
NPC1 O15118 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34474199 0.95 KMT2A (0.69) KMT2AALDH1A1ELANESMN1; SMN2LMNA
SCHEMBL13879509 0.82 KMT2A (0.91) KMT2AALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL11830598 0.80 KMT2A (0.58) KMT2AALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL11773467 0.76 KMT2A (0.57) KMT2AALDH1A1ELANELMNAMAPK1
SCHEMBL11446830 0.75 POLB (0.49) KMT2AALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL3249503 0.73 KMT2A (0.75) KMT2AALDH1A1ELANESMN1; SMN2LMNA
SCHEMBL11453870 0.73 ELANE (0.70) KMT2AALDH1A1ELANESMN1; SMN2MEN1
SCHEMBL21225405 0.72 KMT2A (0.51) KMT2AELANEMEN1
Hydrochloric Acid SCHEMBL23610493 0.72 KMT2A (0.73) KMT2AALDH1A1ELANESMN1; SMN2LMNA
SCHEMBL3233520 0.72 KMT2A (0.73) KMT2AALDH1A1ELANESMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP claimed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US claimed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US claimed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO claimed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US claimed
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US disclosed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US disclosed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed