Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464878 | 0.83 | POLB (0.46) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11445776 | 0.82 | POLB (0.45) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11445913 | 0.82 | POLB (0.45) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11464869 | 0.76 | POLB (0.42) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6549403 | 0.75 | KMT2A (0.77) | KMT2AALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL11446008 | 0.75 | PTGS1 (0.43) | POLBKMT2ALMNA | |
| SCHEMBL6550304 | 0.75 | PTGS1 (0.43) | POLBKMT2ALMNA | |
| SCHEMBL11484794 | 0.70 | POLB (0.57) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10304450 | 0.69 | POLB (0.62) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11808078 | 0.69 | KMT2A (0.63) | POLBKMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208522-A | POLYMER STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4125517-A | ULTRAVIOLET RADIATION | CIBA-GEIGY CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |
| US-4051137-A | Substituted piperazine diones and polymeric compositions stabilized thereby | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |