SCHEMBL6549476

SCHEMBL6549476

Cc1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCCO/N=C/c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
UNG P13051 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
PPARG P37231 4/20 0.35
PPARA Q07869 4/20 0.35
KDM4E B2RXH2 1/20 0.34
FAAH O00519 9/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549482 1.00 UNG (0.36) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6548311 0.99 HDAC1 (0.37) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6548317 0.99 HDAC1 (0.37) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6548204 0.98 PPARG (0.35) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6548207 0.98 PPARG (0.35) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6547281 0.93 UNG (0.39) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6547276 0.93 UNG (0.39) UNGHDAC1HDAC2PPARGPPARA
SCHEMBL6549543 0.92 MAPT (0.38) HDAC1HDAC2PPARGPPARAKDM4E
SCHEMBL6549536 0.92 MAPT (0.38) HDAC1HDAC2PPARGPPARAKDM4E
SCHEMBL6549756 0.92 UNG (0.38) UNGHDAC1HDAC2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 UNG 3162/4885HDAC1 549/4885HDAC2 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.