SCHEMBL6549654

SCHEMBL6549654

N#CC([NH])c1cccc(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
ALDH1A1 P00352 2/20 0.36
BCAT1 P54687 1/20 0.33
BCHE P06276 1/20 0.32
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29095954 0.78 CES2 (0.41) CES2CES1ALDH1A1BCAT1BCHE
SCHEMBL27263318 0.76 CES2 (0.47) CES2CES1ALDH1A1BCAT1BCHE
SCHEMBL16951668 0.76 CES2 (0.40) CES2CES1ALDH1A1BCAT1BCHE
SCHEMBL953145 0.76 CES2 (0.40) CES2CES1ALDH1A1BCAT1BCHE
SCHEMBL953306 0.72 CES2 (0.37) CES2CES1ALDH1A1BCAT1GAA
SCHEMBL10859313 0.72 CES2 (0.37) CES2CES1ALDH1A1BCAT1
SCHEMBL10079576 0.69 CES2 (0.41) CES2CES1ALDH1A1BCHE
SCHEMBL16956757 0.69 CES2 (0.47) CES2CES1BCHE
SCHEMBL19716587 0.68 CES2 (0.34) CES2CES1ALDH1A1BCAT1
SCHEMBL28045728 0.68 CES2 (0.52) CES2CES1ALDH1A1BCHEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1366026-B1 PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed