Ciaftalan

Ciaftalan

SCHEMBL6550047

[Yb].c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21.c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
TDP1 Q9NUW8 4/20 0.45
RECQL P46063 2/20 0.45
THRB P10828 1/20 0.45
APEX1 P27695 1/20 0.45
BLM P54132 1/20 0.45
CA5A P35218 1/20 0.40
GSK3B P49841 1/20 0.38
CDK5 Q00535 1/20 0.38
CDK5R1 Q15078 1/20 0.38
HSD17B10 Q99714 4/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C19 P33261 3/20 0.35
USP2 O75604 1/20 0.35
ALOX15 P16050 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
ALDH1A1 P00352 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciaftalan SCHEMBL6517429 1.00 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
SCHEMBL813083 0.98 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL29360952 0.98 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL29356273 0.98 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL1728179 0.98 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL5795179 0.98 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL15816 0.98 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL223248 0.96 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL9313457 0.96 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL15992891 0.96 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202786-A Spaced apart partially reflecting mirrors having cavity between filled with solutions of rare earth bis-phthalocyanine to control intensity and wavelength of light transmitted THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-04-13 US claimed
JP-60173523-A None JP disclosed
US-10976291-B2 Sensor for determining a measurand dependent upon a concentration of reactive oxygen species ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) 2021-04-13 US disclosed
US-20180156765-A1 SENSOR FOR DETERMINING A MEASURAND DEPENDENT UPON A CONCENTRATION OF REACTIVE OXYGEN SPECIES ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) 2018-06-07 US disclosed
EP-0831358-B1 Liquid crystal devices comprising a multitude of domains having different threshold voltages for switching liquid crystals SONY CORP (JP) 2004-02-04 EP disclosed
EP-0831359-B1 Liquid crystal device comprising a multitude of domains having different threshold voltages for switching liquid crystal SONY CORP (JP) 2003-12-10 EP disclosed
US-6620342-B1 Low solubility; high thermal stability, strength and optical clarity; reversible, electrically controllable light transmission (RECLT) articles ATOFINA CHEMICALS, INC. 2003-09-16 US disclosed
US-6384887-B1 PAIR OF SUBSTRATES HAVING TRANSPARENT ELECTRODES, CARBON BLACK FINE PARTICLES AND AN ALIGNMENT FILM COMPRISING YTTERBIUM DIPHPTHALOCYANINE BETWEEN THE SUBSTRATES SONY CORPORATION (JP) 2002-05-07 US disclosed
EP-1202609-A2 Polyvinylidene fluoride films Atofina Chemicals, Inc. (US) 2002-05-02 EP disclosed
US-6040884-A Liquid crystal devices comprising a multitude of domains having different threshold voltages for switching liquid crystals SONY CORPORATION (JP) 2000-03-21 US disclosed
US-5654784-A Liquid crystal devices comprising a multitude of domains having different threshold voltages for switching liquid crystals SONY CORPORATION (JP) 1997-08-05 US disclosed
EP-0571367-B1 GAS SENSORS AND COMPOUNDS SUITABLE THEREFOR BRITISH TECH GROUP (GB) 1996-09-04 EP disclosed
US-5350459-A Organic photovoltaic element RICOH COMPANY, LTD. (JP) 1994-09-27 US disclosed
EP-0595219-A2 Ferroelectric liquid crystal device SONY CORPORATION (JP) 1994-05-04 EP disclosed
EP-0571367-A1 GAS SENSORS AND COMPOUNDS SUITABLE THEREFOR. BRITISH TECH GROUP (GB) 1993-12-01 EP disclosed
WO-1991007658-A1 GAS SENSORS AND COMPOUNDS SUITABLE THEREFOR BRITISH TECHNOLOGY GROUP LTD. (GB) 1991-05-30 WO disclosed
US-4916470-A Image bar with electrochromic switching system XEROX CORPORATION (US) 1990-04-10 US disclosed
US-4807977-A Multi-color electrochromic cells having solid polymer electrolytes and a distinct electrochromic layer ELTRON RESEARCH, INC. (US) 1989-02-28 US disclosed
US-4750817-A Multi-color electrochromic cells having solid polymer electrolyte layer with organic electrochromic material dissolved therein ELTRON RESEARCH, INC. (US) 1988-06-14 US disclosed
JP-S60173523-A ELECTROCHROMIC DISPLAY DEVICE ASAHI GLASS CO LTD 1985-09-06 JP disclosed