SCHEMBL813083

SCHEMBL813083

c1ccc2c(c1)-c1nc3nc(nc4[nH]c(nc5nc(nc6[nH]c(nc-2n1)c1ccccc61)-c1ccccc1-5)c1ccccc41)-c1ccccc1-3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
RECQL P46063 2/20 0.46
THRB P10828 1/20 0.46
APEX1 P27695 1/20 0.46
BLM P54132 1/20 0.46
CA5A P35218 1/20 0.41
HSD17B10 Q99714 4/20 0.36
CYP1A2 P05177 3/20 0.36
CYP3A4 P08684 3/20 0.36
CYP2D6 P10635 3/20 0.36
CYP2C19 P33261 3/20 0.36
USP2 O75604 1/20 0.36
ALOX15 P16050 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
ALDH1A1 P00352 4/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 3/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciaftalan SCHEMBL15816 1.00 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL29356273 1.00 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL29360952 1.00 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL5795179 1.00 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL1728179 1.00 MEN1 (0.46) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL3199060 0.98 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL11430027 0.98 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL6550047 0.98 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL15992891 0.98 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB
Ciaftalan SCHEMBL22471714 0.98 MEN1 (0.45) MEN1KMT2ATDP1RECQLTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296399-A1 PROCESS FOR PRODUCTION OF POLYLACTIC ACID RESIN COMPOSITION KAO CORP (JP) 2014-10-02 US disclosed
US-8785520-B2 Process for production of polylactic acid resin composition KAO CORPORATION (JP) 2014-07-22 US disclosed
EP-2199052-B1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORP (JP) 2014-01-22 EP disclosed
US-8481620-B2 Process for producing resin composition KAO CORPORATION (JP) 2013-07-09 US disclosed
EP-2345688-B1 PROCESS FOR PRODUCING RESIN COMPOSITION KAO CORP (JP) 2013-03-27 EP disclosed
EP-2532711-A1 PROCESS FOR PRODUCTION OF POLYLACTIC ACID RESIN COMPOSITION Kao Corporation (JP) 2012-12-12 EP disclosed
US-20120296017-A1 PROCESS FOR PRODUCTION OF POLYLACTIC ACID RESIN COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
US-8187891-B2 Methods for detection and determination of vitamin C by luminescence THE UNIVERSITY OF TOKYO (JP) 2012-05-29 US disclosed
US-8062574-B2 Process for production of injection-molded article of polylactic acid resin KAO CORPORATION (JP) 2011-11-22 US disclosed
US-20110196076-A1 PROCESS FOR PRODUCING RESIN COMPOSITION KAO CORPORATION (JP) 2011-08-11 US disclosed
US-5565552-A Method of expanded porphyrin-oligonucleotide conjugate synthesis PHARMACYCLICS, INC. (US) 1996-10-15 US disclosed
US-5543514-A Water-soluble sapphyrins BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1996-08-06 US disclosed
US-5512675-A Methods for preparing porphyrin-like compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1996-04-30 US disclosed
WO-1995029702-A1 TEXAPHYRIN SOLID-SUPPORTS AND DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-11-09 WO disclosed
WO-1995029180-A1 PORPHOCYANINE AND CNC-EXPANDED PORPHYRINS QUADRA LOGIC TECHNOLOGIES INC. (CA) 1995-11-02 WO disclosed
EP-0666859-A1 WAVELENGTH-SPECIFIC PHOTOSENSITIVE PORPHACYANINE AND EXPANDED PORPHYRIN-LIKE COMPOUNDS AND METHODS FOR PREPARATION AND USE THEREOF QUADRA LOGIC TECHNOLOGIES INC. (CA) 1995-08-16 EP disclosed
US-5410045-A As anion chelators, receptors and transporters BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-04-25 US disclosed
US-5405957-A Wavelength-specific photosensitive compounds and expanded porphyrin-like compounds and methods of use THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1995-04-11 US disclosed
WO-1994010172-A1 WAVELENGTH-SPECIFIC PHOTOSENSITIVE PORPHACYANINE AND EXPANDED PORPHYRIN-LIKE COMPOUNDS AND METHODS FOR PREPARATION AND USE THEREOF QUADRA LOGIC TECHNOLOGIES, INC. (CA) 1994-05-11 WO disclosed
US-4097384-A Process for uranium isotope separation NORTHWESTERN UNIVERSITY (US) 1978-06-27 US disclosed