Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536525 | 1.00 | GGPS1 (0.54) | GGPS1KMT2AFNTAFNTB | |
| SCHEMBL9064176 | 1.00 | GGPS1 (0.54) | GGPS1KMT2AFNTAFNTB | |
| SCHEMBL7626511 | 1.00 | GGPS1 (0.54) | GGPS1KMT2AFNTAFNTB | |
| SCHEMBL8539459 | 1.00 | GGPS1 (0.54) | GGPS1KMT2AFNTAFNTB | |
| SCHEMBL6550101 | 1.00 | GGPS1 (0.54) | GGPS1KMT2AFNTAFNTB | |
| SCHEMBL7626203 | 0.86 | FNTA (0.56) | GGPS1FNTAFNTB | |
| SCHEMBL7626199 | 0.86 | FNTA (0.56) | GGPS1FNTAFNTB | |
| SCHEMBL20610011 | 0.84 | GGPS1 (0.56) | GGPS1KMT2AFNTAFNTB | |
| SCHEMBL8771795 | 0.82 | FNTA (0.54) | KMT2AFNTAFNTB | |
| SCHEMBL5179733 | 0.80 | GGPS1 (0.51) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000500758-A | — | — | 2000-01-25 | — | — | JP | claimed |
| EP-0862575-A1 | NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS | LABORATORI BALDACCI Spa (IT) | 1998-09-09 | — | — | EP | claimed |
| EP-0862575-B1 | NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS | BALDACCI LAB SPA (IT) | 2004-02-11 | — | — | EP | disclosed |
| US-6242433-B1 | HAVING ANTIPROLIFERATIVE ACTIVITY IN EUKARYOTIC CELLS WITH RESPECT TO THE INHIBITION OF PROTEIN GERANYGERANYLATION. | LABORATORI BALDACCI SPA (IT) | 2001-06-05 | — | — | US | disclosed |