Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20610011 | 0.96 | GGPS1 (0.56) | GGPS1 | |
| SCHEMBL7626203 | 0.80 | FNTA (0.56) | GGPS1 | |
| SCHEMBL7626511 | 0.80 | GGPS1 (0.54) | GGPS1 | |
| SCHEMBL6550106 | 0.80 | GGPS1 (0.54) | GGPS1 | |
| SCHEMBL7626199 | 0.80 | FNTA (0.56) | GGPS1 | |
| SCHEMBL8539459 | 0.80 | GGPS1 (0.54) | GGPS1 | |
| SCHEMBL9064176 | 0.80 | GGPS1 (0.54) | GGPS1 | |
| SCHEMBL536525 | 0.80 | GGPS1 (0.54) | GGPS1 | |
| SCHEMBL6550101 | 0.80 | GGPS1 (0.54) | GGPS1 | |
| SCHEMBL5068651 | 0.79 | GGPS1 (0.46) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1793832-B1 | GERANYLGERANYL PYROPHOSPHATE SYNTHASE INHIBITORS | UNIV IOWA RES (US) | 2014-07-23 | — | — | EP | disclosed |
| US-7268124-B2 | Geranylgeranyl pyrophosphate synthase inhibitors | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-09-11 | — | — | US | disclosed |
| EP-1793832-A2 | GERANYLGERANYL PYROPHOSPHATE SYNTHASE INHIBITORS | University of Iowa Research (US) | 2007-06-13 | — | — | EP | disclosed |
| US-20060052347-A1 | Geranylgeranyl pyrophosphate synthase inhibitors | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2006-03-09 | — | — | US | disclosed |
| WO-2006026380-A2 | GERANYLGERANYL PYROPHOSPHATE SYNTHASE INHIBITORS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052347-A1 | Geranylgeranyl pyrophosphate synthase inhibitors | GGPS1, FDPS, COASY | GGPS1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.