Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 15/20 | 0.72 |
| ▸ | SRD5A2 | P31213 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | THPO | P40225 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550206 | 1.00 | SRD5A1 (0.72) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL11002514 | 0.89 | SRD5A1 (0.75) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL11002519 | 0.89 | SRD5A1 (0.75) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL2294377 | 0.87 | SRD5A1 (0.78) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL9392056 | 0.87 | SRD5A1 (0.72) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL9392062 | 0.87 | SRD5A1 (0.72) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL2294373 | 0.87 | SRD5A1 (0.78) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL2292660 | 0.87 | SRD5A1 (0.72) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL29207253 | 0.87 | SRD5A1 (0.72) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL2292655 | 0.87 | SRD5A1 (0.72) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116725-B1 | PROCESS FOR OBTAINING 17BETA-(N-TERC-BUTYLCARBAMOYL)-3-ONE-4-AZA-STEROIDS | RAGACTIVES SL (ES) | 2004-01-14 | — | — | EP | disclosed |
| US-6509466-B2 | Reacting 17 beta-(alkoxycarbonyl)-3-one-4-aza-steroid with lithium tert-butylamide in an organic solvent | RAGA CONSULTORES, S.L. (ES) | 2003-01-21 | — | — | US | disclosed |
| US-20010008895-A1 | Process for obtaining 17 beta-(N-tert-butylcarbamoyl)-3-one4-aza-steroids | RAGA CONSULTORES, S.L. | 2001-07-19 | — | — | US | disclosed |
| EP-1116725-A1 | PROCESS FOR OBTAINING 17BETA-(N-TERC-BUTYLCARBAMOYL)-3-ONE-4-AZA-STEROIDS | Raga Consultores, S.L. (ES) | 2001-07-18 | — | — | EP | disclosed |
| WO-1994022900-A1 | AZA-ANDROSTANE-17β-CARBOXAMIDES | CIBA-GEIGY AG (CH) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008895-A1 | Process for obtaining 17 beta-(N-tert-butylcarbamoyl)-3-one4-aza-steroids | CYP17A1, HSD17B7, CYP51A1 | SRD5A1 8/4885SRD5A2 14/4885LMNA 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.