Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184057 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL25899667 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL5704350 | 0.82 | TSHR (0.32) | ALDH1A1TSHRGRM8GRM6GRM7 | |
| SCHEMBL30882164 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL2988734 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNASLC15A2 | |
| SCHEMBL491759 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL816663 | 0.78 | TSHR (0.55) | ALDH1A1TSHRLMNA | |
| SCHEMBL5089365 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL8622494 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL6653916 | 0.78 | TET2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000500758-A | — | — | 2000-01-25 | — | — | JP | claimed |
| EP-0862575-A1 | NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS | LABORATORI BALDACCI Spa (IT) | 1998-09-09 | — | — | EP | claimed |
| CN-117962437-A | Electromagnetic radiation-resistant PVC co-extrusion foaming plate and preparation method thereof | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023202687-A1 | PYRAZINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-10-26 | — | — | WO | disclosed |
| CN-116354932-A | Pyrimidine derivative, preparation method and application thereof | 海思科医药集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-107074836-B | 2-amino-6- (difluoromethyl) -5, 5-difluoro-6-phenyl-3, 4,5, 6-tetrahydropyridine as BACE1 inhibitor | H.隆德贝克有限公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-107074836-A | 2-amino-6- (difluoromethyl) -5, 5-difluoro-6-phenyl-3, 4,5, 6-tetrahydropyridine as BACE1 inhibitor | H.隆德贝克有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-107074810-A | It is used as the tetrahydropyridine of 2 amino 5,5 difluoro 6 (methyl fluoride) 6 phenyl 3,4,5,6 of BACE1 inhibitor | H.隆德贝克有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-102026996-B | Pyridazine derivatives as factor XIA inhibitors | BRISTOL MYERS SQUIBB CO | 2015-01-07 | — | — | CN | disclosed |
| CN-101784516-B | Dipeptide analogs as coagulation factor inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-02 | — | — | CN | disclosed |
| CN-101605779-B | Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor xia inhibitors | SQUIBB BRISTOL MYERS CO US | 2013-11-20 | — | — | CN | disclosed |
| EP-0862575-B1 | NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS | BALDACCI LAB SPA (IT) | 2004-02-11 | — | — | EP | disclosed |
| US-6242433-B1 | HAVING ANTIPROLIFERATIVE ACTIVITY IN EUKARYOTIC CELLS WITH RESPECT TO THE INHIBITION OF PROTEIN GERANYGERANYLATION. | LABORATORI BALDACCI SPA (IT) | 2001-06-05 | — | — | US | disclosed |
| EP-0862575-A1 | NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS | LABORATORI BALDACCI Spa (IT) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019091-A1 | NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS | LABORATORI BALDACCI S.P.A. (IT) | 1997-05-29 | — | — | WO | disclosed |
| US-5510510-A | Inhibitors of farnesyl protein transferase | BRISTOL-MEYERS SQUIBB COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-4591651-A | Process for directly converting an aldehyde into an ethylene ester | AGRIFURANE S.A. (FR) | 1986-05-27 | — | — | US | disclosed |
| EP-0091525-A2 | Phosphonoalkanoylamino acids | ANALYTICAL RESEARCH PHARMACEUTICALS PTY. LTD. (AU) | 1983-10-19 | — | — | EP | disclosed |
| EP-0070131-A1 | Phosphonoalkanoylamino acids | ANALYTICAL RESEARCH PHARMACEUTICALS PTY. LTD. (AU) | 1983-01-19 | — | — | EP | disclosed |
| US-4086208-A | Flame resistant polyesters | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |